NL Journal of Medical and Pharmaceutical Sciences
(ISSN: 3108-0502)

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Impact of Microplastics on the Biological Health of Tilapia (Oreochromis Mossambicus): A Multilevel Toxicological Study

Author(s) : Nivedita Dhumal, Hrishikesh Jawale, Sakshi Mane, Dr. Sanjay Kharat, Dr. Nivedita Das*.
DOI : 10.71168/NMP.02.03.132

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Abstract

Microplastics (MPs) are widespread environmental contaminants known to exert adverse effects on aquatic organisms. This study evaluates the impact of laboratory-prepared MPs on the health of Tilapia (Oreochromis mossambicus) using a multilevel toxicological approach. MPs were characterized by FTIR spectroscopy to confirm polymer identity and examine interactions with tissue homogenates. Exposed groups were compared with controls under controlled conditions. Histological studies revealed tissue-level alterations. Protein expression changes were examined via SDS-PAGE. MP exposure led to significant disruptions, histological damage, and changes in protein profiles. These results demonstrate the potential of MPs to impair organisml level and emphasize the value of integrating physicochemical and biological assessments in evaluating microplastic toxicity. Keywords: FTIR Spectroscopy, Histology, Microplastics, Oreochromis mossambicus, Proteomic profiling.

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